Some health issues have a very long history, and stay with us for millennia. For example, erectile dysfunction. We often explain it by bad ecology, stress, which is a sign of modern times, tiredness and lack of sleep, too much food, etc. However, men suffered from failures in the bedroom in the centuries when there were no television and phones, when their daily schedule depended on the sun, and the world was much simpler and less emotionally draining.
It means that not all intimate ailments have their roots in our polluted environment, or lifestyle. Maybe, the problem lies deeper, in some processes in our bodies? Until recently, people had no idea about it, and tried to cure male sexual impotence with the help of various techniques and remedies — from magical rituals to eating genitals of different animals. Obviously, it did not help much.
Mechanical devices, like pumps and prostheses, that appeared in the 20th century, were better, but men wanted something that did not require the surgeon’s knife, and would not interrupt the intimate process to use the vacuum erection devices. They needed a pill, which would solve their problem without causing any severe side effects. At the very end of the 1980s, the miracle happened, and this revolutionary treatment was discovered.
A Little Bit of History
The company that invented sildenafil — and this is the name of our medicinal product that treats ED — did not have anything like this on their minds in 1989. Pfizer Incorporated was going to help people with the symptoms of ischemic cardiac disease and arterial hypertension. The chemical they were going to use for these purposes showed little to no effectiveness, so the drug was going to be laid on the shelf, if it was not for the unexpected side reaction to the treatment in men.
It appeared that those who could not maintain a boner for a normal sexual act before sildenafil, were surprised to see that their male power is back when they take the tablet. After short consultations, the Pfizer company had decided to trial this medication for the new indication, and that was the luckiest case of the drug repositioning in the history.
We know that the erection happens when the blood fills the cavernous tissues in the penis, making it bigger and harder to be able to penetrate. How does sildenafil facilitate this process? During the research, the scientists have discovered that the whole bunch of chemical reactions in our body are responsible for a boner. We produce nitric oxide when we feel arousal, then it induces the production of cGMP to relax and widen the penis vessels, and finally, when the act is over, we release PDE5 enzyme to bind cGMP and excrete it from the system, which brings penis to its normal state.
Oftentimes, this mechanism works improperly, and PDE5 starts acting too early. And clinical studies have shown that sildenafil inhibits this enzyme and works as a vasodilator, providing a stable and sufficient blood flow to the male organ. Pfizer has proved that this drug works effectively and safely for men who cannot have healthy erection, and patented its preparation under the brand Viagra in 1996. The approval for sales in the US was received in 1998.
Pfizer is still the only company that can produce and sell Viagra in the USA, however, their patent outside the country has expired in 2012, and since that time many companies are manufacturing generics of the blue pill. Centurion Laboratories is one of them, it is located in India, which is one of the world’s leaders in the pharmaceutical industry. Its sildenafil medicine is sold under the trademark Cenforce, you can find the strengths 25, 50, 100, and 200 mg.
What Is Cenforce 50 mg
Cenforce 50 mg is a drug administered mostly for ED treatment. As it relaxes the smooth muscles in our veins, this tablet helps men with prostate enlargement, making urination easier, and mitigates the increased blood pressure in lungs. The main active compound of Cenforce is sildenafil, the tablets look very much alike the brand Viagra — they have the rhombic shape and blue color. The package is white and bright pink, with a black galloping horse and a stamp of the Centurion company. The title says “Sildenafil Citrate Tablets Cenforce-50.” One package contains 100 pills, 10 in a blister.
Due to its main action, it belongs to the group of PDE5 inhibitors, which also includes such famous drugs as vardenafil, tadalafil, avanafil, lodenafil, icariin, etc. The first two from the list are also the top popular ED drugs, traded as Levitra and Cialis, however, Viagra has been the first one and remains the bestseller among them. Cenforce is a generic version of it, which means that it is like a twin brother — different name and clothes, but everything else is the same.
Cenforce tablet has the same working ingredient and excipients:
- magnesium stearate;
- croscarmellose sodium;
- anhydrous dibasic calcium phosphate;
- titanium dioxide;
- microcrystalline cellulose, etc.
The first one is worth our attention, because some people may have lactose intolerance. It is important to make sure that the pill is not going to make things worse.
Viagra vs Cialis vs Levitra
All three most popular ED drugs are oral tablets supplied in different strengths and indicated for the same uses — ED, BPH, and PH, however, tadalafil is the one officially approved for enlarged prostate. The way they work in our body is also the same — they inhibit their target enzyme and increase the blood flow to the penis, making it hard. They all do not like heat or cold, sunlight, and humidity, so it is better to keep them somewhere in a dark place with room temperature, far away from kids, as they all still pose certain risks, especially if taken without a professional control.
The differences of all three are more important:
- time of onset and action. Sildenafil starts working in 30-60 minutes after intake, and remains active in men’s bodies for about 4 hours. Vardenafil will not work sooner than 60 minutes after you take the pill, and will help you keep it hard not longer than for 5 hours. Tadalafil is a champion, as it need only half an hour to start the engine, and the effect will stay with you for a day and a half! It means that if you take the tablet at the Saturday morning, you’ll be able to make love without any worries till Sunday afternoon;
- methods of administration. Neither of these medicines should be taken more than once a day, and in most cases they are used when needed, before the planned intercourse. With one exception, the lowest doses of Cialis can be administered on the daily basis, regardless of the sexual timetable. Such treatment is possible due to the long half-life of the medication, this way you always have tadalafil circulating in your bloodstream and performing its effects;
- the doses. The common recommended dose for Viagra is 50 mg, Cialis and Levitra — 10 mg, the daily dose for Cialis is 2.5 mg. As you see, Cialis and Levitra come in much lower concentrations, thus they are considered to be less dangerous.
As for the prices and availability, you can buy these medications in local pharmacies and online drug stores. The branded pills are not allowed to be sold without a prescription, the costs depend on your insurance and pharmacy. As for the generics, they are available over-the-counter, you can buy them online, and the prices are far lower.
Side Effects and Contraindications
Always remember, that no matter if you are planning to buy the original drug or its generic analogue, you should talk to your doctor before. Also, always read the instructions on the package leaflet, where you can find the information about the correct doses and methods of administrations. Here are the brief guidelines on how to take the Cenforce 50 mg pills safely:
- never mix them with other ED preparations. It may lead to severe consequences, like blood pressure collapse, or painful and long-term erection;
- ask your healthcare provider if you can take tadalafil, and about the correct doses for you, in case you have any cardiovascular, liver, and kidneys issues. Cancer, HIV, recent stroke should also be reported, because you may take meds that cannot be taken together with PDE5 inhibitors;
- you should not use Cenforce if you are on the hypertension or hypotension medications, they interact dangerously. They same applies for some antibiotics and antifungals;
- you should avoid taking ED pills when drinking or using recreational drugs. Together, they can lead to critically decreased blood pressure;
- sildenafil works fine on both empty and full stomach, with one exception — no fatty meals and no grapefruits. The former can postpone the action of the drug, while the latter leads to higher concentration of the chemical compound in blood, which may cause the signs of overdose.
Generic Viagra 50 mg is the initial recommended dose of sildenafil, so it is rather mild and safe. Side effects may occur, but most probably they will pass soon. If you feel headache, nasal stuffiness, flushing, stomach upset, or notice some changes in your vision, this may be related to Viagra intake. Do not ring the alarm at once, but call your doctor if the symptoms do not go away for a long time. In case of Priapism, allergic reactions, hearing loss, and other severe adverse reactions, you should go to the hospital immediately.
Cenforce 50 mg is a safe and effective medication for erectile dysfunction, it is produced by the reputed pharmaceutical company in India, it was checked properly, and approved for sale. This pill will help you the same way Viagra does, with its help you will gain back your sexual powers and happiness. However, buying the branded medicine, you need to go to a doctor and ask for a prescription, which takes time and is rather depressive. Men still do not like to talk about such intimate things.
Come and visit our online drugstore, and you will find your tablets here, available without a prescription. You can make an order right from your home, and pay with credit cards or bitcoins. You do not have to pay a fortune for Viagra, we have pills of the same effects and safety for much lower price. Moreover, you’ll be pleasantly surprised with our bonus program. For example, you will not pay for the delivery if you buy for more than 200 dollars. This is not all we have to offer you. Become our loyal client and forget about your problems!